Clinical Lymphology and Lymphedema
Korean Society of Lymphology and Lymphedema
REVIEW ARTICLE

림프부종 평가를 위한 림프신티그라피: 대한핵의학회/대한림프부종학회 시행/판독 지침 1부

서민석1,*, 한상원2,*, 유민영3, 채선영4, 최준영5,*
Minseok Suh1,*, Sangwon Han2,*, Min Young Yoo3, Sun Young Chae4, Joon Young Choi5,*
1서울대학교병원 핵의학과
2울산대학교 의과대학 서울아산병원 핵의학과
3인하대학교병원 핵의학과
4의정부 을지대학교병원 핵의학과
5성균관대학교 의과대학 삼성서울병원 핵의학과
1Department of Nuclear Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea
2Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
3Department of Nuclear Medicine, Inha University, College of Medicine, Incheon, Republic of Korea
4Department of Nuclear Medicine, Uijeongbu Eulji Medical Center, Eulji University School of Medicine, Uijeongbu-si, Republic of Korea
5Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
*Address for correspondence: Joon Young Choi, MD, PhD, Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, 06351 Seoul, Republic of Korea, Tel: +82-2-3410-2648, Fax: +82-2-3410-2639, E-mail: jynm.choi@samsung.com

Both authors contributed equally.

ⓒ Copyright 2026 Korean Society of Lymphology and Lymphedema. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: Oct 28, 2024; Accepted: Nov 01, 2024

Published Online: Nov 09, 2024

Abatract

Lymphoscintigraphy is a non-invasive imaging technique that visualizes the function and structure of the lymphatic system by administering a radiopharmaceutical subcutaneously, which emits 140 KeV gamma radiation. It plays a crucial role in diagnosing and assessing lymphedema, evaluating disease severity, monitoring therapeutic responses, and predicting prognosis. This procedure involves the use of a gamma camera to capture images of the radiopharmaceutical’s movement through the lymphatic vessels, with the option of utilizing SPECT/CT to enhance anatomical accuracy. Prior to the procedure, it is essential to gather comprehensive clinical information, including the patient’s history of edema, family history, associated syndromes, malignancies, and prior treatments. The Korean Society of Nuclear Medicine and the Korean Society of Lymphedema prepared for the procedure and interpretation guideline of lymphoscintigraphy for lymphedema by consensus. This document included the indications, procedural steps, and technical considerations involved in lymphoscintigraphy for lymphedema among that guideline. Other parts of the guideline will be dealt with by the subsequent paper in the next issue of the journal.

Keywords: Lymphoscintigraphy; Lymphedema; Gamma Camera; 99mTc-phytate