REVIEW ARTICLE

림프계의 신경 조절 기전

윤진아 1 , *
Jin A Yoon 1 , *
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1부산대학교 의과대학 부산대학교병원 재활의학교실
1Department of Rehabilitation Medicine, Pusan National University Hospital, Pusan National University School of Medicine and Biomedical Research Institute, Busan, Republic of Korea
*Address for correspondence: Jin A Yoon, MD, Department of Rehabilitation Medicine, Pusan National University Hospital, Pusan National University School of Medicine, 179 Gudeok-Ro Seo-Gu, Busan 49241, Republic of Korea, Tel: +82-51-240-7480, Fax: +82-51-247-7485, E-mail: yjk5289@naver.com

ⓒ Copyright 2026 Korean Society of Lymphology and Lymphedema. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: Sep 15, 2022; Accepted: Oct 16, 2022

Published Online: Nov 11, 2022

Abatract

The mechanisms regulating lymphatic system are not entirely understood. Generally, there are both extrinsic and intrinsic factors that influence lymph flow. With regard to intrinsic mechanisms, the potential regulation of lymph vessel contractility by the autonomic nervous system has not received much attention thus far. Nerves in close proximity to lymph vessel have been described in humans and large animals, and ex vivo studies have reported responses of the contraction pattern of isolated lymphatic vessels to several neurotransmitters. This review will refer to the known theory of neural control of lymphatic system related to the regulation of lymphatic contractility and circulation.

Keywords: Lymphatic Vessels; Lymphatic System; Innervation